Neurophysiology

Contains a report on a research project.Bell Telephone Laboratories, IncorporatedTeagle FoundationNational Science Foundatio

Neurophysiology

Contains reports on three research projects.National Institutes of Health (Grant 5 ROl NB-04985-04)U. S. Air Force (Aerospace Medical Division) under Contract AF33(615)-3885Bioscience Division of National Aeronautics and Space Administration through Contract NSR 22-009-13

Neurophysiology

Contains reports on two research projects.National Institutes of Health (Grant NB-4897-03)U.S. Air Force (Aerospace Medical Division) under Contract AF33(615)-3885The Teagle Foundation, Inc.Bioscience Division of National Aeronautics and Space Administration, Contract NSR 22-009-13

Neurophysiology

Contains reports on two research projects.National Institutes of Health (Grant 5 ROl NB-04985-04)U. S. Air Force (Aerospace Medical Division) under Contract AF33(615)-3885DSR Project 55-257Bioscience Division of National Aeronautics and Space Administration through Contract NSR 22-009-13

Neurophysiology

Contains reports on four research projects

Neurophysiology

Contains research objectives and reports on one research project.National Institutes of Health (Grant 5 ROl NB-04985-02)National Institutes of Health (Grant 5 RO1 NB-04897-03)U. S. Air Force (Research and Technology Division) under Contract AF33(615)-1747U. S. Air Force (Office of Scientific Research) under Grant AF-AFOSR-880-65National Science Foundation (Grant GP-2495)The Teagle Foundation, Inc.Bell Telephone Laboratories, Inc

Neurophysiology

Contains research objectives and reports on one research project.National Institutes of Health (Grant 5 ROl NB-04985-04)National Institutes of Health (Grant 5 RO1 NB-04897-04)National Institutes of Health (Grant 5 ROl NB-06251-02)National Institutes of Health (Grant 1 505 FR-07047-01)U. S. Air Force (Aerospace Medical Division) under Contract AF33(615)-3885U. S. Air Force (Office of Scientific Research) under Contract F 44620-67-C-0030Bell Telephone Laboratories, In

Neurophysiology

Contains reports on one research project.Teagle FoundationOffice of Naval ResearchBell Telephone Laboratories, Incorporate

Application of single cell transcriptomics to kinetoplastid research

Kinetoplastid parasites are responsible for both human and animal diseases across the globe where they have a great impact on health and economic well-being. Many species and life cycle stages are difficult to study due to limitations in isolation and culture, as well as to their existence as heterogeneous populations in hosts and vectors. Single-cell transcriptomics (scRNA-seq) has the capacity to overcome many of these difficulties, and can be leveraged to disentangle heterogeneous populations, highlight genes crucial for propagation through the life cycle, and enable detailed analysis of host–parasite interactions. Here, we provide a review of studies that have applied scRNA-seq to protozoan parasites so far. In addition, we provide an overview of sample preparation and technology choice considerations when planning scRNA-seq experiments, as well as challenges faced when analysing the large amounts of data generated. Finally, we highlight areas of kinetoplastid research that could benefit from scRNA-seq technologies